| 產(chǎn)品詳情 |
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| Product Name | SGC0946 |
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| Description | A potent and selective DOT1L inhibitor (IC50 = 0. 3 nM in a radioactive enzyme assay); >100-fold selective for other histone methyltransferases (HMTs). SGC0946 also potently reduces H3K79 dimethylation with cellular IC50 of 2.6 nM in A431 cells, and 8.8 nM in MCF10A cells. MW: 618.57. Purity ≥98% by HPLC |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-[3-[[[(2R,3S,4R,5R)-5-(4-Amino-5-?bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydro?xytetrahydrofuran-2-yl]methyl](isopropyl)amino]pro?pyl]-3-[4-(2,2-dimethylethyl)phenyl]urea |
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| Gene, Accession, CAS # | CAS: 1561178-17-3 |
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| Catalog # | 2448-25 |
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| Price | |
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| Order / More Info | SGC0946 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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