| 產(chǎn)品詳情 |
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| Product Name | BAY 87-2243 |
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| Description | BAY 87-2243 is a highly potent and selective inhibitor of hypoxia-induced gene activation. It inhibits HIF-1α and HIF-2α protein accumulation under hypoxic conditions in non-small cell lung cancer (NSCLC) cell line H460 but had no effect on HIF-1α protein levels induced by the hypoxia mimetics desferrioxamine or cobalt chloride. In addition, BAY 87-2243 is also found to act as an inhibitor of mitochondrial function. It can inhibit the oxygen consumption with IC50 value of 10 nM. MW: 525.53. Purity ≥98% by HPLC |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-(1-((2-(4-cyclopropylpiperazin-1-yl)pyridin-4-yl)methyl)-5-methyl-1H-pyrazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole |
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| Gene, Accession, CAS # | CAS: 1227158-85-1 |
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| Catalog # | B1878-25 |
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| Price | |
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| Order / More Info | BAY 87-2243 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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