| 產(chǎn)品詳情 |
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| Product Name | AGN 193109 (sodium salt) |
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| Description | A pan-RAR antagonist (Kd = 2, 2, and 3 nM for RARα, β, and γ, respectively); selective for RARs over RXRs (Kd = >10,000 nM for human RXRα, β, and γ receptors); reverses TTNPB-induced changes in cell morphology in ECE16-1 cells; reverses the growth suppressive effects of all-trans-RA, 13-cis-RA, and 9-cis-RA in ECE16-1 cells when used at a 10-fold molar excess; decreases expression of cytokeratin K5-8, 13, 14, 16, 17, and 19 genes, markers of retinoid action in ECE16-1 cells, when co-administered with TTNPB, but not when used alone; induces cleft palate or frontonasal dysplasia and eye malformations in fetuses of pregnant mice following a single oral dose of 1 mg/kg |
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| Size | 500 μg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CD3106 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 23975-500 |
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| Price | |
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| Order / More Info | AGN 193109 (sodium salt) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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