| 產(chǎn)品詳情 |
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| Product Name | (R)-Bromoenol lactone-d7 |
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| Description | Purity >99%. (R)-Bromoenol lactone-d7 ((R)-BEL-d7 ) contains seven deuterium atoms at the 2, 3, 4, 5, 6, 7, and 8 positions. It is intended for use as an internal standard for the quantification of (R)-BEL by GC- or LC-mass spectrometry (MS). The phospholipases are an extensive family of lipid hydrolases that function in cell signaling, digestion, membrane remodeling, and as venom components. The calcium-independent phospholipase A2 (iPLA2 ) are a PLA2 subfamily closely associated with the release of arachidonic acid in response to physiologic stimuli. (R)-Bromoenol lactone ((R)-BEL) is an irreversible, chiral, mechanism-based inhibitor of iPLA2 Gamma. Unlike (S)-BEL, (R)-BEL does not inhibit iPLA2 Beta except at high doses of 20-30 μM. (R)-BEL inhibits human recombinant iPLA2 Gamma with an IC50 of approximately 0.6 μM. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6E-(bromoethylene)tetrahydro-3R-(1-naphthalenyl-2,3,4,5,6,7,8-d7 )-2H-pyran-2-one, (R)-BEL-d7 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | LS-H5634 |
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| Price | |
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| Order / More Info | (R)-Bromoenol lactone-d7 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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