| 產(chǎn)品詳情 |
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| Antigenic Specificity | ICOS (CD278) |
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| Clone | 15F9 |
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| Host Species | Syrian Hamster |
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| Reactive Species | mouse |
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| Isotype | IgG |
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| Format | allophycocyanin (APC) conjugate |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | APC anti-mouse CD278 (ICOS). CD278 is a 47-57 kD protein, also known as inducible costimulatory molecule (ICOS), or H4. This protein is homologous to the CD28/CTLA-4 proteins. It forms homodimers and is expressed on activated T cells and a subset of thymocytes. It is able to costimulate T cells proliferation. In addition, ICOS has been shown to be involved in humoral immune responses (B cell germinal center formation). The ICOS ligand is B7-H2. ICOS stimulation has been shown to potentiate TCR-mediated IL-4 and IL-10 production and has been proposed to play a role in Th2 cell development. It has also been shown to be involved in airway tolerance and the downregulation of pulmonary inflammation. |
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| Immunogen | n/a |
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| Other Names | Inducible COStimulatory molecule, H4 |
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| Gene, Accession # | Gene ID: 54167 |
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| Catalog # | 107712 |
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| Price | |
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| Order / More Info | ICOS (CD278) Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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