| 產(chǎn)品詳情 |
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| Antigenic Specificity | VISTA |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 20 μL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | VISTA Polyclonal Antibody. VISTA (V-domain Ig containing suppressor of T-cell activation), also known as B7-H5 or PD-H1, is a product of the VSIR gene. Although VISTA bears sequence homology to PD-L1 it has a different expression pattern. In both mouse and humans VISTA is expressed predominantly on hematopoietic cells with the highest densities on CD11b+ myeloid cells, and somewhat lower levels on CD4 and CD8 T cells. VISTA expressed by antigen presenting cells has been shown to directly suppress proliferation and cytokine production of CD4 and CD8 T cells, making it a target for cancer immunotherapy. Mice deficient in VISTA are viable and have elevated frequencies of activated T cells but do not spontaneously develop autoimmune disorders. |
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| Immunogen | n/a |
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| Other Names | 4632428N05Rik, B7-H5, C10orf54, Dies1, Gi24, PD-1H, SISP1, B7H5, B7-H5, C10orf54, chromosome 10 open reading frame 54, GI24, platelet receptor Gi24, PP2135, SISP1, SISP1, stress induced secreted protein 1 |
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| Gene, Accession # | Entrez: 64115, 74048; Uniprot: Q9H7M9 |
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| Catalog # | A305-658A-T |
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| Price | |
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| Order / More Info | VISTA Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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