| 產(chǎn)品詳情 |
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| Product Name | HDAC-5 Inhibitor Screening Kit (Fluorometric) |
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| Description | Histone Deacetylase 5 or HDAC-5 belongs to Class II Histone deacetylase family. It represses transcription by deacetylating lysine residues on the N-terminal part of histones H2A, H2B, H3 and H4. This epigenetic repression caused by HDAC-5, plays a role in transcriptional regulation, cell cycle progression and development. It interacts with myocyte enhancing factor (MEF-2) proteins that are associated with colon cancer, causing the repression of MEF-2 dependent gene expression. HDAC-5 is also involved in epigenetic regulation of ESR1 expression in breast cancer. HDAC-5 inhibition induces reactive oxygen species (ROS) production, ultimately leading to apoptotic cell death as well as mechanisms of mitochondrial quality control processes such |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | ? Screening potential inhibitors of Histone Deacetylase 5? Characterizing/studying HDAC5 inhibitors in plasma samples |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | K171-100 |
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| Order / More Info | HDAC-5 Inhibitor Screening Kit (Fluorometric) from BIOVISION, INC. |
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| Product Specific References | n/a |
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