| Edit |   |
|---|
| Antigenic Specificity | ZAP70 |
|---|
| Clone | A15114B |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human, mouse |
|---|
| Isotype | IgG2b, κ |
|---|
| Format | phycoerythrin (PE) conjugate |
|---|
| Size | 25 tests |
|---|
| Concentration | n/a |
|---|
| Applications | Intracellular Staining for Flow Cytometry (ICFC) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | PE anti-ZAP70. ZAP70 is a 70 kD protein tyrosine kinase associated with the zeta chain of the T cell receptor. It is expressed in T cells and NK cells and has been shown to be involved in T cell signaling. Defects in ZAP70 have been linked to selective T cell defects. The ZAP70 kinase undergoes multiple phosphorylation events after T cell receptor engagement and interacts with a number of proteins involved in signal transduction. Recently, ZAP70 has been identified as an important prognostic marker in B-cell chronic lymphocytic leukemia (B-CLL). |
|---|
| Immunogen | KLH-peptide surrounding ZAP70 Y319. |
|---|
| Other Names | Zeta chain associated protein kinase, SYK related tyrosine kinase, ZAP-70 |
|---|
| Gene, Accession # | Gene ID: 7535 |
|---|
| Catalog # | 691203 |
|---|
| Price | |
|---|
| Order / More Info | ZAP70 Antibody from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|