| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD119 (IFN-g R a chain) |
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| Clone | 2E2 |
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| Host Species | Armenian Hamster |
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| Reactive Species | mouse |
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| Isotype | IgG |
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| Format | biotin conjugate |
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| Size | 500 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Biotin anti-mouse CD119 (IFN-γ R α chain). CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses. |
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| Immunogen | Soluble recombinant mouse IFN-γR α chain protein |
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| Other Names | IFN-γRα , IFN-γ Receptor α chain, CDw119 |
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| Gene, Accession # | Gene ID: 15979 |
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| Catalog # | 112804 |
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| Price | |
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| Order / More Info | CD119 (IFN-g R a chain) Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 20534450,20587787 |
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| 產(chǎn)品資料 |
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