| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Antigenic Specificity | CD126 |
|---|
| Clone | UV4 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human, African green, baboon, cynomolgus, rhesus |
|---|
| Isotype | IgG1, κ |
|---|
| Format | allophycocyanin (APC) conjugate |
|---|
| Size | 25 tests |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry (FC) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | APC anti-human CD126 (IL-6Rα). CD126 is an 80 kD IL-6 receptor α chain also known as IL-6R. It is a member of the immunoglobulin superfamily that is expressed on plasma cells, T cells, activated B cells, monocytes, granulocytes, hepatocytes, epithelial cells, and fibroblasts. Functional IL-6 receptors are formed by the non-covalent association of CD126 and the IL-6 receptor β chain (CD130 or gp130). CD126 binds IL-6 with low affinity but does not signal. The β chain (gp130, CD130) does not bind IL-6 by itself but associates with the α-chain/IL-6 complex to initiate signal transduction. IL-6 binding to the receptor complex results in the stimulation of B and T cells, and hematopoietic precursor proliferation and differentiation. A soluble form of CD126 has been found in human serum. |
|---|
| Immunogen | Human myeloma cell line U266 |
|---|
| Other Names | IL-6Ra, IL-6R1, gp80, IL-6 receptor alpha |
|---|
| Gene, Accession # | Gene ID: 3570 |
|---|
| Catalog # | 352805 |
|---|
| Price | |
|---|
| Order / More Info | CD126 Antibody from BIOLEGEND |
|---|
| Product Specific References | PubMed: 24518760 |
|---|
| 產(chǎn)品資料 |
|
|