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| Antigenic Specificity | CD117 |
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| Clone | 104D2 |
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| Host Species | Mouse |
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| Reactive Species | human, cross-reactivity: cynomolgus, cow |
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| Isotype | IgG1, κ |
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| Format | TotalSeq?-A oligomer conjugate |
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| Size | 10 μg |
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| Concentration | n/a |
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| Applications | Proteogenomics. TotalSeq? reagents are designed to profile protein expression at a single cell level following an optimized protocol similar to the CITE-seq workflow. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TotalSeq?-A0061 anti-human CD117 (c-kit). CD117 is a 145 kD protein tyrosine kinase also known as c-Kit. It is a receptor for stem cell factor or c-Kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells (approximately 1-4% bone marrow cells), mast cells, and acute myeloid leukemia cells (AML). CD117 binding of c-Kit ligand induces phosphorylation of CD117 and stimulates proliferation and survival of primitive hematopoietic stem cells as well as erythroid-committed and granulo-monocytic committed cells. |
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| Immunogen | MOLM-1 megakaryocytic cell line |
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| Other Names | c-KIT, Stem Cell Factor Receptor (SCFR) |
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| Gene, Accession # | Gene ID: 3815 |
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| Catalog # | 313241 |
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| Price | |
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| Order / More Info | CD117 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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