| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Antigenic Specificity | B-Raf Phospho (Thr598/Ser601) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 μl |
|---|
| Concentration | n/a |
|---|
| Applications | Immunofluorescence Microscopy (IF), IHC |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Purified anti-B-Raf Phospho (Thr598/Ser601). The Raf proteins are a family of serine/threonine-specific kinases that serve as a central intermediate in transmitting extracellular signals to the mitogen-activated protein kinase cascade, which controls cell growth, differentiation and survival. Three isoforms of Raf proteins have been found in mammalian cells: Raf-1, A-Raf and B-Raf. The B-raf involved in signal transduction from the membrane to the nucleus. It has been reported that T598 and S601 are the major phosphorylation sites of B-Raf in response to oncogenic Ras, and phosphorylation of these two residues is required for full activation of B-Raf. Mutations in the B-Raf gene have been reported in a number of human cancers, including malignant melanoma, thyroid cancer, and colorectal carcinoma. The poly6327 antibody recognizes human phosphorylated B-Raf (Thr598/Ser601) and has been shown to be useful for immunoflorence staining. |
|---|
| Immunogen | Modified synthetic peptide FGLATVKSRWSGS |
|---|
| Other Names | B-Raf proto-oncogene serine/threonine-protein kinase, BRAF, p94 |
|---|
| Gene, Accession # | n/a |
|---|
| Catalog # | 632702 |
|---|
| Price | |
|---|
| Order / More Info | B-Raf Phospho (Thr598/Ser601) Antibody from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|