| 產(chǎn)品詳情 |
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| Product Name | EIF2B1, 1-305aa, Human, His tag, E.coli |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.1M NaCl. EIF2B1 is one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Phosphorylation of eIF2 inhibits GEF activity of EIF2B, an inhibition that requires the eIF2B1 subunit. Defects in eIF2B1 are a cause of leukoencephalopathy with vanishing white matter (VWM), a brain disease that is characterized by head trauma and motor deterioration. Recombinant human EIF2B1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
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| Size | 50ug, 10ug, |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Eukaryotic translation initiation factor 2B subunit 1 alpha 26kD, Eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kD, EIF-2B, EIF-2Balpha, EIF2B, EIF2BA, MGC117409, MGC125868, MGC125869 |
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| Gene, Accession, CAS # | NP 001405 |
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| Catalog # | ATGP1024 |
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| Order / More Info | EIF2B1, 1-305aa, Human, His tag, E.coli from ATGen |
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| Product Specific References | n/a |
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