| 產(chǎn)品詳情 |
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| Antigenic Specificity | SUMO1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | ELISA, WB, IHC, IF/ICC, FCM, IP. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SUMO1 Antibody is a Rabbit Polyclonal antibody against SUMO1. Small ubiquitin-related modifier 1, 2 and 3 (SUMO-1, -2 and -3) are members of the ubiquitin-like protein familyThe covalent attachment of the SUMO-1, -2 or -3 (SUMOylation) to target proteins is analogous to ubiquitinationThis post-translational modification is a reversible, multi-step process that is initiated by cleaving a precursor protein to a mature proteinMature SUMO-1, -2 or -3 is then linked to the activating enzyme E1, conjugated to E2 and in conjunction with E3, SUMO-1, -2 or -3 is ligated to the target proteinUbiquitin and the individual SUMO family members are all targeted to different proteins with diverse biological functionsUbiquitin predominantly regulates degradation of its targetIn contrast, SUMO-1 is conjugated to RanGAP, PML, p53 and IκB-α to regulate nuclear trafficking, formation of subnuclear structures, regulation of transcriptional activity and protein stabilitySUMO-2/-3 forms poly-(SUMO) chains, is conjugated to topoisomerase II and APP, regulates chromosomal segregation and cellular responses to environmental stress, and plays a role in the progression of Alzheimer disease. |
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| Immunogen | A synthetic peptide of human SUMO-1. |
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| Other Names | DAP1; GAP modifying protein 1; GAP-modifying protein 1; GMP1; OFC10; PIC1; SENP2; Sentrin; Small ubiquitin-related modifier 1; SMT3; SMT3 homolog 3; SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae); SMT3C; SMT3H3; SUMO-1; SUMO1; Ubiquitin-homology domain protein PIC1; Ubiquitin-like protein SMT3C; Ubiquitin-like protein UBL1; UBL1; DAP-1; SMALL UBIQUITIN-LIKE MODIFIER 1; suppressor of mif two 3 homolog 1 (yeast); YEAST; HOMOLOG 3; UBIQUITIN-LIKE 1 |
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| Gene, Accession # | SUMO1, Gene ID: 7341, SwissProt: P63165 |
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| Catalog # | abx117219 |
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| Price | |
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| Order / More Info | SUMO1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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