產(chǎn)品名稱(chēng) AMG 853 from TOCRIS BIOSCIENCE
產(chǎn)品貨號(hào) 5701/10
產(chǎn)品價(jià)格 現(xiàn)貨詢(xún)價(jià)，電話(huà)：010-67529703
產(chǎn)品規(guī)格 10 mg
產(chǎn)品品牌 TOCRIS BIOSCIENCE
產(chǎn)品概述
產(chǎn)品詳情
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Product NameAMG 853
DescriptionPotent dual CRTH2 and prostaglandin D2 (PGD2) receptor antagonist (IC50 values are 8 and 35 nM, respectively in plasma). Inhibits PGD2-induced down modulation of CRTH2 on CD16- granulocytes in human whole blood as well as PGD2-induced cAMP response in platelets. Inhibits PGD2-induced airway constriction in vivo. Also inhibits BRD4 (Kd = 170 nM). Orally bioavailable. Purity 98%. MW (observed): 609.49
Size10 mg
Concentrationn/a
Applicationsn/a
Other Names5-Chloro-4-[2-[[(2-chloro-4-cyclopropylphenyl)sulfonyl]amino]-4-[[(1,1-dimethylethyl)amino]carbonyl]phenoxy]-2-fluorobenzeneacetic acid
Gene, Accession, CAS #CAS: 1169483-24-2
Catalog #5701/10
Price
Order / More InfoAMG 853 from TOCRIS BIOSCIENCE
Product Specific Referencesn/a
產(chǎn)品資料
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