| 產(chǎn)品詳情 |
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| Product Name | Recombinant Human Disintegrin and metalloproteinase domain-containing protein 15 (ADAM15), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 53.6kDa. Extracellular Domain: 207-452aa. N-terminal GST-tagged. Homo sapiens (Human). Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. Cleaves E-cadherin in response to growth factor deprivation. Plays a role in glomerular cell migration. Plays a role in pathological neovascularization. May play a role in cartilage rodeling. May be proteolytically processed, during sperm epididymal maturation and the acrosome reaction. May play a role in sperm-egg binding through its disintegrin domain |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Metalloprotease RGD disintegrin protein; Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15; MDC-15Metargidin |
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| Gene, Accession, CAS # | ADAM15, UniProt: Q13444 |
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| Catalog # | RPC23982 |
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| Price | |
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| Order / More Info | Recombinant Human Disintegrin and metalloproteinase domain-containing protein 15 (ADAM15), partial from BIOMATIK |
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| Product Specific References | n/a |
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