| 產(chǎn)品詳情 |
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| Product Name | Prostatic Acid Phosphatase, Recombinant, Human, 6-His-Tag |
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| Description | Purity ~95% by SDS-PAGE under reducing conditions and visualized by colloidial Coomassie Blue stain at 5ug per lane. Prostatic Acid Phosphatase (ACPP) catalyzes the hydrolysis of a variety of phosphate monoesters, including phosphorylated proteins. The activity optimum of ACPP is in the pH range of 4-6, and the activity is inhibited by L(+)-tartrate. ACPP expression levels are highest in the prostate, with much lower expression in most other tissues. ACPP is a type I integral membrane protein of the plasma membrane and lysosomes, and a secreted form also exists. The concentration of ACPP is elevated in the circulation of prostate cancer patients, making the enzyme a marker for the progression of prostate cancer. Cellular ACPP has been shown to be a protein tyrosine phosphatase. Protein substrates include the epidermal growth factor receptor and HER-2. Cellular ACPP is considered to function as a tumor suppressor. Recombinant corresponding to aa1-379 from human ACPP, fused to 6-His-tag |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Prostatic Acid Phosphatase, Recombinant, Human, 6-His-Tag (5'-nucleotidase, 5'-NT, Ecto-5'-nucleotidase, Thiamine Monophosphatase, TMPase, ACPP) |
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| Gene, Accession, CAS # | SwissProt: P15309 |
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| Catalog # | P9054-75C |
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| Price | |
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| Order / More Info | Prostatic Acid Phosphatase, Recombinant, Human, 6-His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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