| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | Recombinant Naja kaouthia Cobra venom factor, partial |
|---|
| Description | Purity > 90% as determined by SDS-PAGE. MW: 55.4kDa. Partial: 733-984aa. N-terminal GST-tagged. Naja kaouthia (Monocled cobra) (Naja siamensis). Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely resistant to the actions of complement regulatory factors H (CFH) and I (CFI). Therefore, CVF continuously activates complement resulting in the depletion of complement activity. |
|---|
| Size | 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | RUO |
|---|
| Other Names | Complement C3 homolog |
|---|
| Gene, Accession, CAS # | UniProt: Q91132 |
|---|
| Catalog # | RPC20298 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Naja kaouthia Cobra venom factor, partial from BIOMATIK |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|