| 產(chǎn)品詳情 |
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| Product Name | Recombinant Human Interleukin-11 protein (IL11) (Active) |
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| Description | Purity > 95% as determined by SDS-PAGE and HPLC. MW: 19.1kDa. Full Length of Mature Protein: 22-199aa. tag-Free. Homo sapiens (Human). Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. {ECO:0000250|UniProtKB:P47873, ECO:0000269|PubMed:12919066, ECO:0000269|PubMed:2145578}. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | IL-11, AGIF, Oprelvekin |
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| Gene, Accession, CAS # | IL11, UniProt: P20809 |
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| Catalog # | RPC26499 |
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| Price | |
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| Order / More Info | Recombinant Human Interleukin-11 protein (IL11) (Active) from BIOMATIK |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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