| 產(chǎn)品詳情 |
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| Product Name | Recombinant Human Integrin-linked protein kinase (ILK), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 30kDa. Partial: 1-228aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | 59KDA serine/threonine-protein kinaseILK-1ILK-2p59ILK |
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| Gene, Accession, CAS # | ILK, UniProt: Q13418 |
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| Catalog # | RPC23939 |
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| Order / More Info | Recombinant Human Integrin-linked protein kinase (ILK), partial from BIOMATIK |
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| Product Specific References | n/a |
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