| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD66a |
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| Clone | MAb-CC1 |
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| Host Species | Mouse |
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| Reactive Species | mouse |
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| Isotype | IgG1, κ |
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| Format | Brilliant Violet 421? conjugate |
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| Size | 50 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Brilliant Violet 421? anti-mouse CD66a (CEACAM1a). CD66a, known as CEACAM1a, carcinoembryonic antigen-related cell adhesion molecule 1a, is a glycoprotein of the immunoglobulin superfamily and the carcinoembryonic antigen family. Isoforms expressing either two or four alternatively spliced Ig-like domains in mice have been found in a number of epithelial, endothelial, or hematopoietic tissues. CEACAM1a functions as an intercellular adhesion molecule, an angiogenic factor, and a tumor cell growth inhibitor. It also serves as a signal regulatory protein influencing B cell receptor complex-mediated activation. The mouse and human CEACAM1a proteins are targets of viral or bacterial pathogens, respectively. It was reported that targeted disruption of the CEACAM1a gene resulting in a partial ablation of the protein in mice led to reduced susceptibility to virus infection. The antibody recognizes the N-terminal domain of murine CEACAM1a, it does not recognize murine CEACAM1b, an allele in SJL mice. |
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| Immunogen | SJL/J mice immunized with deoxycholate extracted proteins from BALB/c intestinal brush border membranes. |
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| Other Names | CEACAM1a, Bgp |
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| Gene, Accession # | Gene ID: 26365 |
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| Catalog # | 134531 |
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| Price | |
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| Order / More Info | CD66a Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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