| 產(chǎn)品詳情 |
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| Product Name | Recombinant Escherichia coli dITP/XTP pyrophosphatase (rdgB) |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 41kDa. Full Length: 1-197aa. N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged. Escherichia coli (strain K12). Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Can also efficiently hydrolyze 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP). Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.To a much lesser extent,is also able to hydrolyze GTP, dGTP and dUTP, but shows very low activity toward the canonical nucleotides dATP, dCTP and dTTP and toward 8-oxo-dGTP, purine deoxyribose triphosphate, 2-aminopurine deoxyribose triphosphate and 2,6-diaminopurine deoxyribose triphosphate |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Deoxyribonucleoside triphosphate pyrophosphohydrolase1; Inosine triphosphate pyrophosphatase1; ITPase1; Non-canonical purine NTP pyrophosphataseUniRule annotation1; Non-standard purine NTP pyrophosphataseUniRule annotation1; Nucleoside-triphosphate diphosphataseUniRule annotation1; Nucleoside-triphosphate pyrophosphataseUniRule annotation1; NTPase; yggV |
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| Gene, Accession, CAS # | rdgB, UniProt: P52061 |
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| Catalog # | RPC22624 |
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| Order / More Info | Recombinant Escherichia coli dITP/XTP pyrophosphatase (rdgB) from BIOMATIK |
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| Product Specific References | n/a |
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