| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD300a |
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| Clone | TX41 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, κ |
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| Format | purified, azide-free |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), IP, Activ |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Ultra-LEAF? Purified anti-mouse CD300a. CD300 receptors are a group of type I transmembrane proteins, which belong to the Ig superfamily. In mice, nine members have been reported with different nomenclature systems, such as myeloid-associated Ig-like receptor (MAIR), leukocyte mono-Ig-like receptor (LMIR), DC-derived Ig-like receptor (DIgR), and CMRF-35-like molecule (CLM). The CD300 molecules act as either activating or inhibitory receptors through interactions with adaptor molecules, such as PAD12, DAP10, and FcRγ. CD300a is an inhibitory receptor that is mainly expressed on peripheral eosinophils, mast cells, neutrophils, dendritic cells, macrophages, and some B cells. Cross-linking CD300a by an antibody can induce phosphorylation of tyrosine residues in the cytoplasmic domain, which results in recruitment of phosphatases SHIP, SHP1 and SHP2 and inhibition of cell activation. |
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| Immunogen | MAIR-I transfected |
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| Other Names | MAIR-I, LMIR-I, LMIR1, CLM-8, CLM8, CMRF-35H, IRp60, MMAC8, PIGR4, MCPIR1 |
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| Gene, Accession # | Gene ID: 217303 |
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| Catalog # | 147901 |
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| Price | |
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| Order / More Info | CD300a Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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