| 產(chǎn)品詳情 |
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| Product Name | DAA1106 |
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| Description | A TSPO agonist (IC50 = 0.28 nM in a radioligand binding assay); selective for TSPO over CBR and GABAA receptors in rat whole brain membranes, as well as a panel of 54 ion channels, uptake/transporters, and secondary messenger receptors at concentrations greater than 10 μM; increases mitochondrial prognenolone formation in rat brain homogenates, which indirectly potentiates GABAA receptor signaling; increases the time mice spend in the light area of the light/dark exploration and the time rats spend in open arms of the elevated plus maze in a dose-dependent manner, suggesting a decrease in anxiety-like behavior; radiolabeled versions have been synthesized to study the distribution of PBRs in neurological disease models using PET |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | DAA-1106 |
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| Gene, Accession, CAS # | CAS: 220551-92-8 |
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| Catalog # | 23454-10 |
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| Price | |
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| Order / More Info | DAA1106 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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