| 產(chǎn)品詳情 |
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| Product Name | HLA-DRB1,30-227aa, Human, His tag, E.coli (Denatured) |
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| Description | Purity: > 85% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol . HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; exon 4 encodes the transmembrane domain; and exon 5 encodes the cytoplasmic tail. Recombinant human HLA-DRB1 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
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| Size | 0.5mg, 100ug, 20ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Major histocompatibility complex class II DR beta 1, Major histocompatibility complex, class II, DR beta 1, DRB1, HLA DRB1, HLA-DR1B, HLA-DRB1 |
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| Gene, Accession, CAS # | NP 002115 |
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| Catalog # | ATGP2585 |
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| Order / More Info | HLA-DRB1,30-227aa, Human, His tag, E.coli (Denatured) from ATGen |
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| Product Specific References | n/a |
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