| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | Recombinant Human Terminal nucleotidyltransferase 4A (TENT4B) |
|---|
| Description | Purity > 85% as determined by SDS-PAGE. MW: 67.3kDa. Full Length: 1-572aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Catalytic subunit of a TRAMP-like complex which has a poly RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity. Required for cytoplasmic polyadenylation of mRNAs involved in carbohydrate metabolism, including the glucose transporter SLC2A1/GLUT1. Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion. Mediates 3' adenylation of the microRNA MIR21 followed by its 3'-to-5' trimming by the exoribonuclease PARN leading to degradation. Mediates 3' adenylation of H/ACA box snoRNAs followed by its 3'-to-5' trimming by the exoribonuclease PARN which enhances snoRNA stability and maturation. |
|---|
| Size | 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | RUO |
|---|
| Other Names | PAP-associated domain-containing protein 5 (Terminal nucleotidyltransferase 4B) (Terminal uridylyltransferase 3) (TUTase 3) (Topoisomerase-related function protein 4-2) (TRF4-2) (GLD4) (PAPD5) (TRF4-2) |
|---|
| Gene, Accession, CAS # | TENT4B, UniProt: Q8NDF8 |
|---|
| Catalog # | RPC26068 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Human Terminal nucleotidyltransferase 4A (TENT4B) from BIOMATIK |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|